Histological assessment in peripheral nerve tissue engineering
نویسندگان
چکیده
منابع مشابه
Experimental Approaches on Tissue Engineering Repair of Peripheral Nerve Gaps
Peripheral nerve research is highly dynamic and a current major focus is the development of cell based supportive therapies as well as bioengineered nerve conduits to overcome the challenges in reconstructing long peripheral nerve defects. Whenever primary nerve repair cannot be performed without regeneration impairing tension at the suture sites, autologous nerve grafting or nerve tubulization...
متن کاملRepairing peripheral nerve injury using tissue engineering techniques
Each year approximately 360,000 people in the United States suffer a peripheral nerve injury (PNI), which is a leading source of lifelong disability (Kelsey et al., 1997; Noble et al., 1998). The most frequent cause of PNIs is motor vehicle accidents, while gunshot wounds, stabbings, and birth trauma are also common factors. Patients suffering from disabilities as a result of their PNIs are als...
متن کاملNeural tissue engineering options for peripheral nerve regeneration.
Tissue engineered nerve grafts (TENGs) have emerged as a potential alternative to autologous nerve grafts, the gold standard for peripheral nerve repair. Typically, TENGs are composed of a biomaterial-based template that incorporates biochemical cues. A number of TENGs have been used experimentally to bridge long peripheral nerve gaps in various animal models, where the desired outcome is nerve...
متن کاملTissue-engineered Peripheral Nerve
Nerve injuries occur by a variety of mechanisms, including traumatic wounds, thermal or chemical damage, myelin or axonal degeneration, and acute compression. These injuries typically result in the loss of motor function, sensory function, or both. Functional recovery is regained upon complete axonal regeneration, which includes remyelination and reinnervation (i.e., synapse formation) of the a...
متن کاملAn anatomical study of porcine peripheral nerve and its potential use in nerve tissue engineering
Current nerve tissue engineering applications are adopting xenogeneic nerve tissue as potential nerve grafts to help aid nerve regeneration. However, there is little literature that describes the exact location, anatomy and physiology of these nerves to highlight their potential as a donor graft. The aim of this study was to identify and characterise the structural and extracellular matrix (ECM...
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ژورنال
عنوان ژورنال: Neural Regeneration Research
سال: 2014
ISSN: 1673-5374
DOI: 10.4103/1673-5374.141798